Quadrupole ion trap time-of-flight MALDI mass spectrometry: hydration of the ions of hydroxyl-containing compounds
T16N1
D.S. Kosyakov, O. Yu. Khoroshev, E.A. Anikeenko, N.V. Ul’yanovskii
On the example of a number of natural hydroxyl-containing compounds of various classes the possibility of artifact formation, associated with ion hydration, in the quadrupole ion trap MALDI mass spectra is shown for the first time. It was established that when using tandem mass spectrometry, both precursor ions and product ions are involved in the formation of water adducts. The main source of water for ion-molecular interactions in the ion trap are buffer and collision gases. The role of metal cations in the formation of analytes adducts with water is noted. For the majority of studied hydroxyl-containing compounds, hydration proceeds most actively during cationization with lithium ions, with the peak of the [M+H2O+Li]+ ion dominating in the mass spectra.
