Non-target screening of markers of synthetic cannabinoids in urine using HPLC-MS/MS
T12N1
Non-target screening of markers of synthetic cannabinoids in urine
using HPLC-MS/MS
A.V. Labutin, A.Z. Temerdashev
A method of non-target screening for determination of some synthetic cannabinoids and their metabolites in biological samples has been suggested. It was based on the preservation of the basic structure of the analytes in samples. The discussed two approaches included the identification of known compound metabolites with the aid of high-resolution mass spectra and target screening of characteristic product ions of the most common classes of psychoactive compounds. The possibility of applying the proposed approach were examined on the real samples of biological fluids of people used such synthetic cannabinoids as AM(N)-2201 and AB-PINACA.
