Features of the first and second order electrospray ionization mass spectra of salt-like products derived from mono and diols with the aid of combined reagents on the basis of ω-bromoacyl chlorides and nitrogen bases
T14N2
V.V. Ilyushenkova, L.N.Kulikova, R.S. Borisov, V.G. Zaikin
The paper describes the results of application of derivatization by composite reagents on the basis of ω-bromoacyl chlorides [ClCO(CH2)nBr (n=1-4)] and pyridine for the investigation of aliphatic and alicyclic alcohols and diols by ordinary and tandem electrospray/ionization (ESI) mass spectrometry. The applied derivatization involves the simultaneous acylation of hydroxyl groups by acyl chloride part of a reagent and quaternization of pyridine by bromoalkyl end group. Under the ESI conditions, quaternary salts produce corresponding mono and diammonium cations that appear in first order mass spectra. Collision induced dissociation (CID) of primary cations generated from monool derivatives gives rise to ammonium cations of corresponding acids HOOC(CH2)n-N+(C5H5). CID of primary dications gives rise to the same cations which are also eliminated from dications to form mono-charged fragments.
