High-resolution time of flight mass spectrometry combined with high performance liquid chromatography for detection and determination of quinolones and sulfonamides in foods
T12N2
V.G. Amelin, A.I. Korotkov, N.M. Volkova
Method of high-resolution time-of-flight mass spectrometry combined with high performance liquid chromatography has been developed for the detection and determination of residues of 23 quinolones (fluoroquinolones) and a number of sulfonamides in foods. The samples were prepared using simplified and quick sample preparation. The limits of detection of quinolones and sulfonamides ranged from 0.05 (1) to 1000 (2000) mkg kg‒1. A scheme for identification and determination of detected quinolones has been developed using method of standard addition. The relative standard deviations of analysis results are less than 0.1.
